ALDH6A1 antibody (C-Term)

Catalog No. ABIN356979

This anti-ALDH6A1 antibody is a Rabbit Polyclonal antibody detecting ALDH6A1 in WB and EIA. Suitable for Human.

Quick Overview for ALDH6A1 antibody (C-Term) (ABIN356979)

Target: ALDH6A1 (Aldehyde Dehydrogenase 6 Family, Member A1 (ALDH6A1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH6A1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-ALDH6A1 Antibody

Binding Specificity: C-Term

Specificity: This antibody detects ALDH6A1 at C-term.

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide selected from the C-terminal region of human ALDH6A1

Isotype: Ig Fraction

Application Details

Application Notes: ELISA 1: 1,000. Western blot 1: 50 - 1: 100. Immunohistochemistry 1: 10 - 1: 50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for ALDH6A1

Target: ALDH6A1 (Aldehyde Dehydrogenase 6 Family, Member A1 (ALDH6A1))

Alternative Name: ALDH6A1 / MMSDH

Background: ALDH6A1 belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. This protein is a mitochondrial methylmalonate semialdehyde dehydrogenase, and catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.Synonyms: Aldehyde dehydrogenase family 6 member A1, Malonate-semialdehyde dehydrogenase [acylating], Methylmalonate-semialdehyde dehydrogenase [acylating] mitochondrial

Molecular Weight: 57858Da

Gene ID: 4329, 9606

UniProt: Q02252

Pathways: Brown Fat Cell Differentiation