P-Cadherin antibody (N-Term)

Catalog No. ABIN357038

The Rabbit Polyclonal anti-P-Cadherin antibody has been validated for IHC (p) and EIA. It is suitable to detect P-Cadherin in samples from Human.

Quick Overview for P-Cadherin antibody (N-Term) (ABIN357038)

Target: P-Cadherin (CDH3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P-Cadherin antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-P-Cadherin Antibody

Binding Specificity: N-Term

Specificity: This antibody detects CDH3 at N-term.

Purification: Protein A column, followed by peptide affinity purification

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human CDH3.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA 1: 1,000. Immunohistochemistry 1: 10 - 1: 50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for P-Cadherin

Target: P-Cadherin (CDH3)

Alternative Name: Cadherin-3

Background: CDH3 is a classical cadherin from the cadherin superfamily. It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in the gene encoding CDH3 have been associated with congential hypotrichosis with juvenile macular dystrophy.Synonyms: CDH3, CDHP, Cadherin P, P-Cadherin, Placental cadherin

Molecular Weight: 91418 Da

Gene ID: 1001, 9606

UniProt: P22223