BMP3 antibody (N-Term)

Catalog No. ABIN357181

This Rabbit Polyclonal antibody specifically detects BMP3 in WB, IHC (p) and EIA. It exhibits reactivity toward Human.

Quick Overview for BMP3 antibody (N-Term) (ABIN357181)

Target: BMP3 (Bone Morphogenetic Protein 3 (BMP3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMP3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-BMP3 Antibody

Binding Specificity: N-Term

Specificity: This antibody reacts to BMP3.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human Bmp3.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Immunohistochemistry: 1/50 - 1/100. Western blotting: 1: 500
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for BMP3

Target: BMP3 (Bone Morphogenetic Protein 3 (BMP3))

Alternative Name: BMP3

Background: The BMPs belong to the TGF-Beta superfamilyBMPs stimulate the production of bone matrix proteins and thereby alter stromal cell and osteoclast proliferation, a key step in bone marrow development. In addition to promoting ectopic bone and cartilage development, BMPs regulate the growth, differentiation, chemotaxis, proliferation, and apoptosis of various cell types, including mesenchymal cells, epithelial cells, hematopoietic cells, and neuronal cells. BMPs also play a role in dorsal/ventral patterning. BMP3, highly expressed in lung, ovary and small intestine, participates in cartilage and bone formation. BMP3 and BMP2 genes map to conserved regions between human and mouse.Synonyms: BMP-3A, BMP3A, Bone morphogenetic protein 3, Osteogenin

Gene ID: 651, 9606

UniProt: P12645