Neurogenin 3 antibody (N-Term)

Catalog No. ABIN357411

Product Details anti-Neurogenin 3 Antibody

Target: Neurogenin 3 (NEUROG3)

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Neurogenin 3 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects Neurogenin3 at N-term.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human Neurogenin3.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA 1: 1,000. Western blot 1: 100 - 1: 500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for Neurogenin 3

Target: Neurogenin 3 (NEUROG3)

Alternative Name: Neurogenin-3 (NEUROG3 Products)

Synonyms: NEUROG3 antibody, ngn3 antibody, atoh5 antibody, ngn-3 antibody, bhlha7 antibody, math4b antibody, neurog3 antibody, Ngn3 antibody, Atoh5 antibody, Math4B antibody, NGN-3 antibody, bHLHa7 antibody, Relax antibody, atoh4 antibody, ngn2 antibody, ngn3a antibody, neurogenin 3 antibody, neurogenin 3 S homeolog antibody, neurogenin-3 antibody, NEUROG3 antibody, neurog3 antibody, neurog3.S antibody, Tsp_02556 antibody, Neurog3 antibody

Background: Neurogenin-3 belongs to a family of basic helix-loop-helix transcription factors involved in the determination of neural precursor cells in the neuroectoderm. Neurogenin-3 also required for the specification of a common precursor of the 4 pancreatic endocrine cell types. Defects in NEUROG3 are the cause of congenital malabsorptive diarrhea 4 (DIAR4). DIAR4 is an autosomal recessive disorder characterized by generalized malabsorption and a paucity of enteroendocrine cells.Synonyms: ATOH5, BHLHA7, Class A basic helix-loop-helix protein 7, NEUROG3, NGN-3, NGN3, Protein atonal homolog 5

Molecular Weight: 22968 Da

Gene ID: 50674, 9606

UniProt: Q5VVI0