AMFR antibody (N-Term)

Catalog No. ABIN357584

The Rabbit Polyclonal anti-AMFR antibody has been validated for WB, IHC (p) and EIA. It is suitable to detect AMFR in samples from Human.

Quick Overview for AMFR antibody (N-Term) (ABIN357584)

Target: AMFR (Autocrine Motility Factor Receptor (AMFR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AMFR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-AMFR Antibody

Binding Specificity: N-Term

Specificity: This antibody is specific to AMFR (N-term).

Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human AMFR.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for AMFR

Target: AMFR (Autocrine Motility Factor Receptor (AMFR))

Alternative Name: AMFR / RNF45

Background: Autocrine motility factor (AMF) is a protein secreted by tumor cells that stimulates tumor motility. The gene for AMFR encodes a 323-amino acid polypeptide that has a single transmembrane domain and several putative glycosylation sites. The protein sequence has some homology to human tumor protein p53.Synonyms: AMF receptor isoform 2, Autocrine motility factor receptor isoform 2, RING finger protein 45, gp78

Molecular Weight: 34325 Da

Gene ID: 267

NCBI Accession: NP_001135

UniProt: Q9UKV5

Pathways: ER-Nucleus Signaling