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ARL3 antibody (C-Term)

ARL3 Reactivity: Human WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN357652
  • Target See all ARL3 Antibodies
    ARL3 (ADP-Ribosylation Factor-Like 3 (ARL3))
    Binding Specificity
    • 15
    • 9
    • 8
    • 7
    • 7
    • 4
    • 3
    • 1
    C-Term
    Reactivity
    • 64
    • 12
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 58
    • 6
    Rabbit
    Clonality
    • 60
    • 4
    Polyclonal
    Conjugate
    • 23
    • 6
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This ARL3 antibody is un-conjugated
    Application
    • 41
    • 31
    • 16
    • 13
    • 13
    • 6
    • 6
    • 3
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody is specific to ARL3 (C-term).
    Purification
    Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ARL3.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product ARL3 Primary Antibody
  • Application Notes
    ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium Azide as preservative.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    ARL3 (ADP-Ribosylation Factor-Like 3 (ARL3))
    Alternative Name
    ARL3 (ARL3 Products)
    Synonyms
    ARFL3 antibody, si:ch211-208d15.4 antibody, wu:fj22g05 antibody, arfl3 antibody, arl3 antibody, ADP ribosylation factor like GTPase 3 antibody, ADP-ribosylation factor-like 3 antibody, ADP ribosylation factor like GTPase 3 S homeolog antibody, ADP-ribosylation factor-like protein 3 antibody, ARL3 antibody, arl3 antibody, Arl3 antibody, arl3.1.S antibody, arl-3 antibody
    Background
    ADP-ribosylation factors (ARFs) are low molecular weight GTP-binding proteins belonging to the RAS superfamily. The predicted 182-amino acid ARL3 (ADP-ribosylation like factor) protein shares 97 % amino acid identity with rat ARLl3 and 43 % identity with human ARF1. Like the ARFs, ARL3 has a glycine at position 2, the site of N myristoylation, and lacks cysteine residues near the C terminus, which are found in other members of the RAS family. Northern blot analysis detected a 1-kb ARL3 transcript in all tissues tested, with highest expression in heart and lung, and lower expression in brain, liver, kidney, ovary, and testis. A 5.5-kb transcript was also detected in most tissues, with highest expression in brain. Immunoblot analysis detected ARL3 in human tumor cell lines but not in normal rodent cells. Although ARL3 binds GTP, it is devoid of activity in the cholera toxin-dependent ADP-ribosylation of Gs, and is therefore classified as an ARF-like protein.Synonyms: ADP-ribosylation factor-like protein 3, ARFL3
    Molecular Weight
    20455 Da
    Gene ID
    403, 9606
    UniProt
    P36405
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