MARCKS antibody (C-Term)

Catalog No. ABIN357762

The Rabbit Polyclonal anti-MARCKS antibody (ABIN357762) specifically detects MARCKS in WB and EIA. The antibody is reactive with Human samples.

Quick Overview for MARCKS antibody (C-Term) (ABIN357762)

Target: MARCKS (Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MARCKS antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-MARCKS Antibody

Binding Specificity: AA 247-276, C-Term

Specificity: This antibody is specific to Human MARCKS (C-term).

Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: KLH conjugated synthetic peptide between 247~276 amino acids from the C-terminal region of human MARCKS

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for MARCKS

Target: MARCKS (Myristoylated Alanine-Rich Protein Kinase C Substrate (MARCKS))

Alternative Name: MARCKS

Background: MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.Synonyms: MACS, Myristoylated alanine-rich C-kinase substrate, PRKCSL

Molecular Weight: 31413 Da

Gene ID: 4082

NCBI Accession: NP_002347

UniProt: P29966