ACOX1 antibody (N-Term)

Catalog No. ABIN357764

Product Details anti-ACOX1 Antibody

Target: ACOX1 (Acyl-CoA Oxidase 1, Palmitoyl (ACOX1))

Binding Specificity: N-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACOX1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody is specific to ACOX1 (N-term).

Cross-Reactivity (Details): Species reactivity (tested):Human and Mouse.

Purification: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human ACOX1.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western Blot: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for ACOX1

Target: ACOX1 (Acyl-CoA Oxidase 1, Palmitoyl (ACOX1))

Alternative Name: ACOX1 (ACOX1 Products)

Synonyms: zgc:92584 antibody, wu:fb59h12 antibody, zgc:114033 antibody, aco antibody, acox antibody, ACOX antibody, PALMCOX antibody, SCOX antibody, RATACOA1 antibody, AOX antibody, Acox antibody, D130055E20Rik antibody, Paox antibody, PCOX1 antibody, acyl-CoA oxidase 1 antibody, acyl-CoA oxidase 1, palmitoyl antibody, acyl-CoA oxidase 1, palmitoyl L homeolog antibody, acyl-Coenzyme A oxidase 1, palmitoyl antibody, ACOX1 antibody, acox1 antibody, acox1.L antibody, Acox1 antibody

Background: ACOX1 is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids.Synonyms: AOX, Palmitoyl-CoA oxidase, Peroxisomal acyl-coenzyme A oxidase 1, Straight-chain acyl-CoA oxidase

Molecular Weight: 74442 Da

Gene ID: 51, 9606

UniProt: Q15067

Pathways: Regulation of Lipid Metabolism by PPARalpha, Monocarboxylic Acid Catabolic Process