SMC2 antibody (C-Term)

Catalog No. ABIN357820

This Rabbit Polyclonal antibody specifically detects SMC2 in WB and EIA. It exhibits reactivity toward Human.

Quick Overview for SMC2 antibody (C-Term) (ABIN357820)

Target: SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMC2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-SMC2 Antibody

Binding Specificity: C-Term

Specificity: This antibody detects SMC2 (C-term).

Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human SMC2.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western Blot: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for SMC2

Target: SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))

Alternative Name: SMC2 / CAPE

Background: SMC2 is a central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.Synonyms: CAP-E, Chromosome-associated protein E, SMC protein 2, SMC-2, SMC2L1, Structural maintenance of chromosomes protein 2, XCAP-E homolog

Molecular Weight: 135656 Da

Gene ID: 10592

NCBI Accession: NP_001036015

UniProt: O95347