TNIK antibody (pSer764)

Catalog No. ABIN358244

The Rabbit Polyclonal anti-TNIK antibody is suitable to detect TNIK in samples from Human. It has been validated for IHC (p) and EIA.

Quick Overview for TNIK antibody (pSer764) (ABIN358244)

Target: TNIK (TRAF2 and NCK Interacting Kinase (TNIK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNIK antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-TNIK Antibody

Binding Specificity: pSer764

Specificity: This antibody detects TNIK pSer764.

Purification: Protein G Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S764 of human TNIK.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Immunohistochemistry: 1/50-1/100. Dot Blot: 1/100-1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for TNIK

Target: TNIK (TRAF2 and NCK Interacting Kinase (TNIK))

Alternative Name: TNIK

Background: TNIK is a stress-activated serine/threonine kinase that may play a role in the response to environmental stress. This protein appears to act upstream of the JUN N-terminal pathway, and may play a role in cytoskeletal regulation.Synonyms: KIAA0551, TRAF2 and NCK-interacting protein kinase

Molecular Weight: 154943 Da

Gene ID: 23043, 9606

UniProt: Q9UKE5