Leptin antibody (C-Term)
Quick Overview for Leptin antibody (C-Term) (ABIN358628)
Target
See all Leptin (LEP) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 138-167, C-Term
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Specificity
- This antibody recognizes Human Leptin (LEP).
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Purification
- Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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Immunogen
- KLH conjugated synthetic peptide between 138~167 amino acids from the C-terminal region of Human Leptin . Genename: LEP
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Isotype
- Ig Fraction
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Application Notes
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ELISA: 1/1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Avoid repeated freezing and thawing.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Leptin (LEP)
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Alternative Name
- Leptin
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Background
- Leptin (LEP) is an adipocyte-secreted protein that regulates body fat and endocrine functions. Leptin is similar to the mouse obesity protein encoded by the obese gene (ob). In mouse studies, mutations in this gene are linked to severe and morbid obesity.Synonyms: LEP, OB, OBS, Obese protein, Obesity factor
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Gene ID
- 3952, 9606
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UniProt
- P41159
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Pathways
- JAK-STAT Signaling, AMPK Signaling, Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Monocarboxylic Acid Catabolic Process
Target
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