MAGE-Like 2 antibody (N-Term)

Catalog No. ABIN358645

This Rabbit Polyclonal antibody specifically detects MAGE-Like 2 in WB, IHC (p) and EIA. It exhibits reactivity toward Human.

Quick Overview for MAGE-Like 2 antibody (N-Term) (ABIN358645)

Target: MAGE-Like 2 (MAGEL2)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGE-Like 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-MAGE-Like 2 Antibody

Binding Specificity: N-Term

Specificity: This antibody reacts to MAGEA2.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human MAGEA2.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for MAGE-Like 2

Target: MAGE-Like 2 (MAGEL2)

Alternative Name: MAGE-2

Background: MAGEA2 is a member of the MAGEA gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 80 % sequence identity between each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are expressed at a high level in a number of tumors of various histologic types, and are silent in normal tissues with the exception of testis and placenta. The MAGEA genes are clustered on chromosome Xq28. They may be implicated in some hereditary disorders, such as dyskeratosis congenita. This gene has two identical copies at different loci.Synonyms: Cancer/testis antigen 1.2, MAGE 2, MAGE2, MAGEA2, MAGEA2A, Melanoma-associated antigen 2

Gene ID: 266740, 9606

UniProt: P43356