MAGEH1 antibody (C-Term)

Catalog No. ABIN358661

The Rabbit Polyclonal anti-MAGEH1 antibody is suitable to detect MAGEH1 in samples from Human. It has been validated for WB, IHC (p) and EIA.

Quick Overview for MAGEH1 antibody (C-Term) (ABIN358661)

Target: MAGEH1 (Melanoma Antigen Family H, 1 (MAGEH1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MAGEH1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-MAGEH1 Antibody

Binding Specificity: C-Term

Specificity: This antibody reacts to MAGEH1.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human MAGEH1.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for MAGEH1

Target: MAGEH1 (Melanoma Antigen Family H, 1 (MAGEH1))

Alternative Name: MAGE-H1

Background: Melanoma-associated antigen (MAGE) are completely silent in normal tissues, with the exception of male germ cells, and, for some of them, placenta. These antigens ought to be strictly tumor specific, expressed in tumor cells of various histological types. Because of their specific expression on tumor cells, these antigens are of particular interest for antitumor immunotherapy. Genes of the MAGE family direct the expression of tumor antigens that are recognized on a human melanoma by autologous cytolytic T lymphocytes. Though the function of MAGEH1 is not fully elucidated, it may play a role in embryonal development and tumor transformation or aspects of tumor progression.Synonyms: APR1, Apoptosis-related protein 1, MAGEH1, Melanoma-associated antigen H1, Restin

Gene ID: 28986, 9606

UniProt: Q9H213

Pathways: Neurotrophin Signaling Pathway