ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Format
Liquid
Concentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Target
MLLT1
(MLLT1, super elongation complex subunit (MLLT1))
MGC84026 antibody, MLLT1 antibody, ENL antibody, LTG19 antibody, YEATS1 antibody, AA407901 antibody, BAM11 antibody, MLLT1, super elongation complex subunit antibody, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1 L homeolog antibody, myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1 antibody, Mllt1 antibody, MLLT1 antibody, mllt1.L antibody, mllt1 antibody
Background
Chromosome band 11q23 is the site of translocations in myeloid and lymphoid acute leukemias, pediatric leukemias, and treatment-induced secondary acute myelogenous leukemia. The translocation breakpoints cluster in a restricted region of the HRX gene resulting in chimeric genes that encode an N-terminal portion of Hrx fused to various partner proteins. Myeloid/lymphoid or mixed-lineage leukemia translocated to 1 (MLLT1) is a nuclear protein with transcriptional transactivation properties that is fused to Hrx in t(11,19) leukemias. The minimal MLLT1 sequence required for transcription activation was narrowed to the C-terminal 90 amino acids.Synonyms: LTG19, YEATS domain-containing protein 1, YEATS1, mixed-lineage leukemia translocated to 1