AGR2 antibody (AA 102-132)

Catalog No. ABIN358784

Product Details anti-AGR2 Antibody

Target: AGR2 (Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2))

Binding Specificity: AA 102-132

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGR2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to Anterior Gradient 2 (AGR2).

Purification: Protein A column, followed by peptide affinity purification

Immunogen: KLH conjugated synthetic peptide between 102~132 amino acids from the Center region of Human AGR2.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for AGR2

Target: AGR2 (Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2))

Alternative Name: AGR2 (AGR2 Products)

Synonyms: AG2 antibody, GOB-4 antibody, HAG-2 antibody, PDIA17 antibody, XAG-2 antibody, Agr2h antibody, Gob-4 antibody, mAG-2 antibody, wu:fj29g05 antibody, zgc:112187 antibody, agr2 antibody, hag3 antibody, hag-3 antibody, bcmp11 antibody, MGC89004 antibody, XAgr2 antibody, agr2-A antibody, anterior gradient 2, protein disulphide isomerase family member antibody, anterior gradient 2 antibody, anterior gradient 3, protein disulphide isomerase family member antibody, anterior gradient 2, protein disulphide isomerase family member S homeolog antibody, AGR2 antibody, Agr2 antibody, agr2 antibody, agr3 antibody, agr2.S antibody

Background: Anterior gradient 2 (AGR2) is known as a cancer cell marker specifically up-regulated in response to depletion of serum and oxygen. AGR2 has been identified as a tumor marker in primary and secondary cancer lesions, and as a marker for detection of circulating tumor cells (CTCs). Elevated levels of AGR2 are known to increase the metastatic potential of cancer cells, but conditions leading to increased expression of AGR2 are not well understood.Synonyms: AG-2, AG2, Anterior gradient protein 2 homolog, HPC8, Secreted cement gland protein XAG-2 homolog

Gene ID: 10551, 9606

UniProt: O95994