IL1RL2 antibody (C-Term)

Catalog No. ABIN358951

This Rabbit Polyclonal antibody specifically detects IL1RL2 in WB and EIA. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for IL1RL2 antibody (C-Term) (ABIN358951)

Target: IL1RL2 (Interleukin 1 Receptor-Like 2 (IL1RL2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL1RL2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-IL1RL2 Antibody

Binding Specificity: C-Term

Specificity: This antibody reacts to IL1R.

Purification: Protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal(E487) region of human IL1R.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000 . Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-IL1RL2 antibody (ABIN358951)

De Marco, Lappano, De Francesco, Cirillo, Pupo, Avino, Vivacqua, Abonante, Picard, Maggiolini: "GPER signalling in both cancer-associated fibroblasts and breast cancer cells mediates a feedforward IL1β/IL1R1 response." in: Scientific reports, Vol. 6, pp. 24354, (2017) (PubMed).

Target Details for IL1RL2

Target: IL1RL2 (Interleukin 1 Receptor-Like 2 (IL1RL2))

Alternative Name: IL1RL2 / IL1RRP2

Background: IL1R is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. IL1R is a receptor for interleukin 1 family member 9 (IL1F9). Binding to the agonist leads to the activation of NF-kappa-B. The gene for this protein and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor 1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.Synonyms: IL-1Rrp2, Interleukin-1 receptor-like 2, Interleukin-1 receptor-related protein 2

Gene ID: 8808, 9606

UniProt: Q9HB29