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TGIF1 antibody (Middle Region)

TGIF1 Reactivity: Human WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN359523
  • Target See all TGIF1 Antibodies
    TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))
    Binding Specificity
    • 9
    • 8
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 49
    • 14
    • 11
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 42
    • 6
    • 1
    Rabbit
    Clonality
    • 44
    • 5
    Polyclonal
    Conjugate
    • 28
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TGIF1 antibody is un-conjugated
    Application
    • 34
    • 27
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects TGIF at center.
    Purification
    PBS with 0.09% (W/V) sodium azide
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human TGIF1.
    Isotype
    Ig Fraction
    Top Product
    Discover our top product TGIF1 Primary Antibody
  • Application Notes
    ELISA 1: 1,000. Western blot 1: 50 - 1: 100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • Target
    TGIF1 (TGFB-Induced Factor Homeobox 1 (TGIF1))
    Alternative Name
    TGIF1 (TGIF1 Products)
    Synonyms
    HPE4 antibody, TGIF antibody, AA959811 antibody, AI462167 antibody, Tgif antibody, Tfig antibody, fa06h05 antibody, fb33g11 antibody, zgc:55852 antibody, wu:fa06h05 antibody, wu:fb33g11 antibody, hpe4 antibody, tgif antibody, tgif1 antibody, TGFB induced factor homeobox 1 antibody, TGFB-induced factor homeobox 1 antibody, TGFB induced factor homeobox 1 S homeolog antibody, TGIF1 antibody, Tgif1 antibody, tgif1 antibody, tgif1.S antibody
    Background
    TGIF1 is a member of the three-amino acid loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain.Synonyms: 5'-TG-3'-interacting factor 1, Homeobox protein TGIF1, TGIF
    Molecular Weight
    43044 Da
    Gene ID
    7050, 9606
    UniProt
    Q15583
    Pathways
    Retinoic Acid Receptor Signaling Pathway, Chromatin Binding, Tube Formation
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