HIPK3 antibody (C-Term)

Catalog No. ABIN359692

This Rabbit Polyclonal antibody specifically detects HIPK3 in IHC (p) and EIA. It exhibits reactivity toward Human.

Quick Overview for HIPK3 antibody (C-Term) (ABIN359692)

Target: HIPK3 (Homeodomain Interacting Protein Kinase 3 (HIPK3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HIPK3 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-HIPK3 Antibody

Binding Specificity: C-Term

Specificity: This antibody reacts to HIPK3.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the sequence of human HIPK3 within a 1100-1200.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for HIPK3

Target: HIPK3 (Homeodomain Interacting Protein Kinase 3 (HIPK3))

Alternative Name: HIPK3 / FIST / ANPK

Background: HIPK3 negatively regulates apoptosis by promoting FADD phosphorylation. This kinase enhances androgen receptor-mediated transcription, and may act as a transcriptional corepressor for NK homeodomain transcription factors.Synonyms: Androgen receptor-interacting nuclear protein kinase, DYRK6, FIST3, Fas-interacting serine/threonine-protein kinase, Homeodomain-interacting protein kinase 3, Homolog of protein kinase YAK1, PKY

Gene ID: 10114, 9606

UniProt: Q9H422