STK4 antibody (C-Term)

Catalog No. ABIN360312

The Rabbit Polyclonal anti-STK4 antibody (ABIN360312) specifically detects STK4 in WB, IHC (p) and EIA. The antibody is reactive with Human samples.

Quick Overview for STK4 antibody (C-Term) (ABIN360312)

Target: STK4 (serine/threonine Kinase 4 (STK4))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STK4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-STK4 Antibody

Binding Specificity: C-Term

Specificity: This antibody reacts to MST1.

Purification: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human MST1.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for STK4

Target: STK4 (serine/threonine Kinase 4 (STK4))

Alternative Name: STK4

Background: MST1 is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it is possible that this protein induces the chromatin condensation observed in this process.Synonyms: MST-1, MST1, Mammalian STE20-like protein kinase 1, STE20-like kinase MST1, STE20-like kinase MST1, Serine/threonine-protein kinase 4, Serine/threonine-protein kinase Krs-2

Gene ID: 6789, 9606

UniProt: Q13043

Pathways: Tube Formation