GARS antibody (C-Term)

Catalog No. ABIN360353

The Rabbit Polyclonal anti-GARS antibody is suitable to detect GARS in samples from Human. It has been validated for WB and EIA.

Quick Overview for GARS antibody (C-Term) (ABIN360353)

Target: GARS (Glycyl-tRNA Synthetase (GARS))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GARS antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-GARS Antibody

Binding Specificity: C-Term

Specificity: This antibody reacts to GARS.

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human GARS.

Isotype: Ig Fraction

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Target Details for GARS

Target: GARS (Glycyl-tRNA Synthetase (GARS))

Alternative Name: Glycyl-tRNA Synthetase

Background: GARS is a glycyl-tRNA synthetase, one of the aminoacyl-tRNA synthetases that charge tRNAs with their cognate amino acids. This protein is an (alpha)2 dimer which belongs to the class II family of tRNA synthetases. The protein has been shown to be a target of autoantibodies in the human autoimmune diseases, polymyositis or dermatomyositis.Synonyms: AP-4-A synthetase, Diadenosine tetraphosphate synthetase, GARS, GlyRS, Glycine-tRNA ligase, SMAD1

Gene ID: 2617, 9606

UniProt: P41250

Pathways: Ribonucleoside Biosynthetic Process