EDAR antibody (Extracellular Domain)
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- Target See all EDAR Antibodies
- EDAR (Ectodysplasin A Receptor (EDAR))
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Binding Specificity
- Extracellular Domain
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Reactivity
- Human, Mouse
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- This EDAR antibody is un-conjugated
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Application
- Western Blotting (WB)
- Specificity
- This antibody detects EDAR and cross reacts with human EDAR.
- Purification
- Protein A/G affinity chromatography
- Immunogen
- Recombinant extracellular domain of EDAR
- Clone
- 9A38
- Isotype
- IgG2
- Top Product
- Discover our top product EDAR Primary Antibody
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- Application Notes
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Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Reconstitution
- Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Target
- EDAR (Ectodysplasin A Receptor (EDAR))
- Alternative Name
- EDAR (EDAR Products)
- Synonyms
- rs3 antibody, edar antibody, EDAR antibody, MGC88893 antibody, DL antibody, ECTD10A antibody, ECTD10B antibody, ED1R antibody, ED3 antibody, ED5 antibody, EDA-A1R antibody, EDA1R antibody, EDA3 antibody, HRM1 antibody, dl antibody, RGD1561714 antibody, ectodysplasin A receptor antibody, ectodysplasin-A receptor antibody, edar antibody, EDAR antibody, Edar antibody
- Background
- EDAR (Ectodysplasin A receptor) is a receptor for EDA isoform A1, but not for EDA isoform A2. It has a single transmembrane domain, and shows similarity to 2 separate domains of the tumor necrosis factor (TNF) receptor (TNFR) family. It mediates the activation of NF-kappa-B and JNK and may promote caspase independent cell death. Defects in EDAR are a cause of hypohidrotic ectodermal dysplasia.Synonyms: Anhidrotic ectodysplasin receptor 1, DL, Downless homolog, ED1R, ED3, ED5, EDA-A1 receptor, EDA-A1R, EDA1R, EDA3, Ectodermal dysplasia receptor, Ectodysplasin-A receptor, FLJ94390, HRM1, Tumor necrosis factor receptor superfamily member EDAR
- Gene ID
- 13608
- NCBI Accession
- NP_034230
- UniProt
- Q9R187
- Pathways
- Tube Formation, Ubiquitin Proteasome Pathway
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