IL-10RA antibody (Extracellular Domain)

Catalog No. ABIN360911

The Hamster Monoclonal anti-IL-10RA antibody is suitable to detect IL-10RA in samples from Mouse. It has been validated for WB.

Quick Overview for IL-10RA antibody (Extracellular Domain) (ABIN360911)

Target: IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

Reactivity: Mouse

Host: Hamster

Clonality: Monoclonal

Conjugate: This IL-10RA antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 9-00E-012

Product Details anti-IL-10RA Antibody

Binding Specificity: Extracellular Domain

Specificity: This antibody detects IL-10Ralpha.

Purification: Protein A/G affinity chromatography

Immunogen: Recombinant protein of IL-10Ralpha extracellular domain.

Isotype: IgG2

Application Details

Application Notes: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 200 μL sterile PBS and the final concentration is 500 μg/mL.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for IL-10RA

Target: IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

Alternative Name: CDw210a / IL10RA

Background: Interleukin 10 binds specifically and with high affinity to cell-surface receptors. Interleukin 10 receptors are members of the class II subgroup of the cytokine receptor superfamily. The IL10 receptor complex contains two distinct type II cytokine receptor subunits, the ligand binding IL10RA and the IL10RB. The coexpression of both chains is essential for IL10 induced signal transduction. The beta chain serves as an accessory chain essential for the active IL10 receptor complex and necessary for the initiation of signal transdunction. Interleukin 10 receptors are expressed in all cell types that are known to respond to IL10.Synonyms: IL-10R-A, IL10 Receptor alpha, Interleukin-10 receptor alpha chain

Gene ID: 16154

NCBI Accession: NP_032374

UniProt: Q61727

Pathways: Growth Factor Binding