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Actin antibody

ACTA1 Reactivity: Chicken WB, IHC, IF Host: Mouse Monoclonal C4 unconjugated
Catalog No. ABIN361349
  • Target See all Actin (ACTA1) Antibodies
    Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))
    Reactivity
    • 96
    • 44
    • 43
    • 17
    • 12
    • 9
    • 9
    • 8
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Chicken
    Host
    • 81
    • 30
    Mouse
    Clonality
    • 76
    • 33
    Monoclonal
    Conjugate
    • 62
    • 12
    • 12
    • 10
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Actin antibody is un-conjugated
    Application
    • 90
    • 57
    • 39
    • 28
    • 26
    • 25
    • 10
    • 9
    • 7
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    Specificity
    Specific for the ~42 kDa actin protein in lysates from skeletal, cardiac, gizzard and aorta tissues. Reacts with all actin isoforms.
    Cross-Reactivity
    All Species
    Purification
    Ascites fluid
    Immunogen
    Preparation of chicken gizzard actin
    Clone
    C4
    Isotype
    IgG1
    Top Product
    Discover our top product ACTA1 Primary Antibody
  • Application Notes
    Recommended Dilution: WB:1:5,000 IF: 1:500 IHC: 1:500 Quality Control: Western blots performed on each lot.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Ascites fluid + 0.01 % Sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
  • Wheaton, Aten, Queiroz, Sullivan, Oberdick, Hoyt, Obrietan: "Circadian expression and functional characterization of PEA-15 within the mouse suprachiasmatic nucleus." in: The European journal of neuroscience, Vol. 47, Issue 7, pp. 845-857, (2019) (PubMed).

    Choi, Horning, Aten, Karelina, Alzate-Correa, Arthur, Hoyt, Obrietan: "Mitogen- and Stress-Activated Protein Kinase 1 Regulates Status Epilepticus-Evoked Cell Death in the Hippocampus." in: ASN neuro, Vol. 9, Issue 5, pp. 1759091417726607, (2018) (PubMed).

    Barcus, OLeary, Brockman, Rugowski, Liu, Garcia, Yu, Keely, Eliceiri, Schuler: "Elevated collagen-I augments tumor progressive signals, intravasation and metastasis of prolactin-induced estrogen receptor alpha positive mammary tumor cells." in: Breast cancer research : BCR, Vol. 19, Issue 1, pp. 9, (2017) (PubMed).

    Ramena, Yin, Yu, Walia, Elble: "CLCA2 Interactor EVA1 Is Required for Mammary Epithelial Cell Differentiation." in: PLoS ONE, Vol. 11, Issue 3, pp. e0147489, (2016) (PubMed).

    Barcus, Holt, Keely, Eliceiri, Schuler: "Dense collagen-I matrices enhance pro-tumorigenic estrogen-prolactin crosstalk in MCF-7 and T47D breast cancer cells." in: PLoS ONE, Vol. 10, Issue 1, pp. e0116891, (2016) (PubMed).

  • Target
    Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))
    Alternative Name
    ACTA1 (ACTA1 Products)
    Synonyms
    ACTA antibody, ASMA antibody, CFTD antibody, CFTD1 antibody, CFTDM antibody, MPFD antibody, NEM1 antibody, NEM2 antibody, NEM3 antibody, acta antibody, asma antibody, cftd antibody, cftd1 antibody, cftdm antibody, mpfd antibody, nem1 antibody, AA959943 antibody, Acta-2 antibody, Acts antibody, Actsk-1 antibody, actc antibody, actc1 antibody, cfk antibody, hm:zeh0631 antibody, zeh0631 antibody, acta1 antibody, hm:zeh0293 antibody, zgc:112098 antibody, actin, alpha 1, skeletal muscle antibody, actin, alpha 1, skeletal muscle L homeolog antibody, actin, alpha 1b, skeletal muscle antibody, actin, muscle antibody, actin, alpha skeletal muscle antibody, actin, alpha 1a, skeletal muscle antibody, ACTA1 antibody, acta1.L antibody, acta1 antibody, Acta1 antibody, acta1b antibody, LOC100533357 antibody, LOC109479779 antibody, LOC109108280 antibody, acta1a antibody
    Background
    Actin is the most abundant protein found in virtually all eukaryotic cells. It is also one of the most highly-conserved proteins, differing by no more than 20% in species as diverse as algae and humans, making it an excellent choice for use as a loading control. It is the monomeric subunit of microfilaments, one of the three major components of the cytoskeleton, and of thin filaments, which are part of the contractile apparatus in muscle cells. Thus, actin participates in many important cellular functions, including muscle contraction, cell motility, cell division and cytokinesis, vesicle and organelle movement, cell signaling, and the establishment and maintenance of cell junctions and cell shape. Anti-Actin Western blot of rat hippocampal homogenate showing specific immunolabeling of the ~ 42k actin protein.
    Molecular Weight
    '42 kDa
    Gene ID
    421534
    UniProt
    P68139
    Pathways
    Caspase Cascade in Apoptosis, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development
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