Calretinin antibody

Catalog No. ABIN361372

Product Details anti-Calretinin Antibody

Target: Calretinin (CALB2) (Calbindin 2 (CALB2))

Reactivity: Guinea Pig

Host: Sheep

Clonality: Polyclonal

Conjugate: This Calretinin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Specificity: Specific for the ~29 kDa Calretinin protein in Western blots. The antibody also works well for immunohistochemistry on formalin or paraformaldehyde perfused rat brain tissue sections. It is expected that this antibody will also react with human, mouse , non-human primates.

Cross-Reactivity: Rat (Rattus)

Predicted Reactivity: human, mouse, non-human primates

Purification: Protein A purified

Immunogen: Purified guinea pig calretinin

Application Details

Application Notes: Recommended Dilution: WB: 1:1,000 IHC: 1:500 Quality Control: Western blots performed on each lot.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 100 μL in 10 mM Tris, 100 mM NaCl

Storage: -20 °C

Target Details for Calretinin

Target: Calretinin (CALB2) (Calbindin 2 (CALB2))

Alternative Name: CALB2 (CALB2 Products)

Synonyms: CAB29 antibody, CAL2 antibody, CR antibody, calb2l antibody, wu:fq18e08 antibody, zgc:73115 antibody, calb2 antibody, wu:fq17g09 antibody, zgc:73099 antibody, calbindin 2 antibody, calbindin 2a antibody, calbindin 2b antibody, CALB2 antibody, Calb2 antibody, calb2a antibody, calb2b antibody

Background: Calretinin is a calcium-binding protein involved in calcium signaling. It is abundantly expressed throughout the central nervous system, retina and many other tissues. Studies have shown that calretinin may play a role in neuroprotection by buffering intracellular calcium (Lukas and Jones 1994, Weisenhorn et al., 1996). Additionally, calretinin selectively stains mesothelial cells thus making it an important marker for differentiating malignant mesothelioma from carcinomas (Attanoos et al., 2000). Anti-Calretinin Western blot of rat cerebellum (CB) lysate showing specific immunolabeling of the ~ 29k calretinin protein.

Molecular Weight: '29 kDa

Gene ID: 117059

UniProt: P47728