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Retinoic Acid Receptor beta antibody (N-Term)

RARB Reactivity: Human WB Host: Mouse Monoclonal 336 unconjugated
Catalog No. ABIN361388
  • Target See all Retinoic Acid Receptor beta (RARB) Antibodies
    Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))
    Binding Specificity
    • 15
    • 10
    • 8
    • 7
    • 7
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 78
    • 36
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    Human
    Host
    • 70
    • 8
    Mouse
    Clonality
    • 72
    • 6
    Monoclonal
    Conjugate
    • 40
    • 7
    • 6
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Retinoic Acid Receptor beta antibody is un-conjugated
    Application
    • 69
    • 42
    • 15
    • 13
    • 13
    • 10
    • 9
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Specificity
    Specific for the ~48k RAR-( isotype.
    Cross-Reactivity
    Human, Rat (Rattus)
    Predicted Reactivity
    canine, guinea pig, mouse, non-human primate
    Purification
    Protein G purified culture supernatant
    Immunogen
    Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH
    Clone
    336
    Isotype
    IgG1
    Top Product
    Discover our top product RARB Primary Antibody
  • Application Notes
    Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.
    Storage
    -20 °C
  • Target
    Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))
    Alternative Name
    RARB (RARB Products)
    Synonyms
    RARB antibody, nRARs antibody, HAP antibody, NR1B2 antibody, RRB2 antibody, A830025K23 antibody, Hap antibody, Nr1b2 antibody, RARbeta2 antibody, RARBETA antibody, retinoic acid receptor beta antibody, retinoic acid receptor, beta antibody, RARB antibody, Rarb antibody
    Background
    Retinoic Acid (RA, active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The Retinoid X receptors (RXRs) family (RXRa, ß and () preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors (RARs). RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005). Anti- Retinoic Acid Receptor, (-Isotype Western blot of hippocampal lysate showing specific immunolabeling of the ~48k RAR-ß isotype.
    Molecular Weight
    '48 kDa
    Gene ID
    5915
    UniProt
    P10826
    Pathways
    Nuclear Receptor Transcription Pathway, Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway
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