GABRG2 antibody (pSer327)

Catalog No. ABIN361470

This anti-GABRG2 antibody is a Rabbit Polyclonal antibody detecting GABRG2 in WB and ELISA. Suitable for Rat. This Primary Antibody has been cited in 1 publication.

Quick Overview for GABRG2 antibody (pSer327) (ABIN361470)

Target: GABRG2 (gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRG2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GABRG2 Antibody

Binding Specificity: pSer327

Specificity: Specific for endogenous levels of the ~45 kDa GABAA receptor γ2 subunit phosphorylated at Ser327. Immunolabeling is blocked by preadsorption with the phosphopeptide used as antigen, but not by the corresponding non-phosphopeptide.

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: bovine, canine, chicken, human, non-human primate

Characteristics: Our GABAA Receptor γ2 (Ser327) rabbit polyclonal phosphospecific primary antibody is produced in-house. It detects GABAA Receptor γ2 (Ser327) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.

Purification: Prepared from pooled rabbit serum by affinity purification via sequential chromatography on phospho and non-phosphopeptide affinity columns.

Immunogen: Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser327 of the gamma2 subunit of rat GABAA receptor, conjugated to keyhole limpet hemocyanin (KLH).

Isotype: IgG

Application Details

Application Notes:

Dilution Range: WB Brain: 1:1000

Dilution Range: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Storage: -20 °C

Storage Comment: Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Expiry Date: 12 months

References for anti-GABRG2 antibody (ABIN361470)

Bohnsack, Carlson, Morrow: "Differential regulation of synaptic and extrasynaptic α4 GABA(A) receptor populations by protein kinase A and protein kinase C in cultured cortical neurons." in: Neuropharmacology, Vol. 105, pp. 124-32, (2016) (PubMed).

Target Details for GABRG2

Target: GABRG2 (gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2))

Alternative Name: GABRG2

Background:

Synonyms: CAE 2 antibody, CAE2 antibody, ECA 2 antibody, ECA2 antibody, GABA(A) receptor gamma 2 antibody, GABA(A) receptor subunit gamma 2 antibody, GABA(A) receptor subunit gamma-2 antibody, GABRγ2 antibody, GABRG2 antibody, Gamma aminobutyric acid (GABA) A receptor gamma 2 antibody, Gamma aminobutyric acid A receptor gamma 2 antibody, Gamma aminobutyric acid receptor gamma 2 subunit antibody, Gamma-aminobutyric acid receptor subunit gamma-2 antibody, GBRG2_HUMAN antibody, GEFSP 3 antibody, GEFSP3 antibody

Description Logic: Our GABAA Receptor γ2 (Ser327) rabbit polyclonal phosphospecific primary antibody is produced . It detects GABAA Receptor γ2 (Ser327) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.

Gene Name Alternatives: GABRG2

Molecular Weight: 45 kDa

Gene ID: 29709

UniProt: P18508