Parkin antibody (pSer378)

Catalog No. ABIN361515

The Rabbit Polyclonal anti-Parkin antibody (ABIN361515) specifically detects Parkin in WB and ELISA. The antibody is reactive with Human samples.

Quick Overview for Parkin antibody (pSer378) (ABIN361515)

Target: Parkin (PARK2) (Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Parkin antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-Parkin Antibody

Binding Specificity: pSer378

Specificity: Specific for the ~52 kDa parkin protein phosphorylated at Ser378. Immunolabeling of the parkin band is absent in parkin S378 mutants.

Cross-Reactivity: Human

Characteristics: Our Parkin (Ser378) rabbit polyclonal phosphospecific primary antibody is produced in-house. It detects Parkin (Ser378) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.

Purification: Prepared from pooled rabbit serum by affinity purification via sequential chromatography on phospho and non-phosphopeptide affinity columns.

Immunogen: Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser378 of human Parkin, conjugated to keyhole limpet hemocyanin (KLH).

Isotype: IgG

Application Details

Application Notes: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Storage: -20 °C

Storage Comment: Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Expiry Date: 12 months

Target Details for Parkin

Target: Parkin (PARK2) (Parkinson Protein 2, E3 Ubiquitin Protein Ligase (Parkin) (PARK2))

Alternative Name: PARK2

Background:

Synonyms: AR JP antibody, E3 ubiquitin ligase antibody, E3 ubiquitin protein ligase parkin antibody, E3 ubiquitin-protein ligase parkin antibody, FRA6E antibody, LPRS 2 antibody, LPRS2 antibody, PARK 2 antibody, Park2 antibody, Parkin 2 antibody, Parkinson disease (autosomal recessive juvenile) 2 antibody, Parkinson disease (autosomal recessive juvenile) 2 parkin antibody, Parkinson disease protein 2 antibody, Parkinson juvenile disease protein 2 antibody, Parkinson protein 2 E3 ubiquitin protein ligase antibody, Parkinson protein 2 E3 ubiquitin protein ligase (parkin) antibody, PDJ antibody, PRKN 2 antibody, PRKN antibody, PRKN2 antibody, PRKN2_HUMAN antibody, Ubiquitin E3 ligase PRKN antibody

Description Logic: Our Parkin (Ser378) rabbit polyclonal phosphospecific primary antibody is produced . It detects Parkin (Ser378) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB.

Gene Name Alternatives: PARK2

Molecular Weight: 52 kDa

Gene ID: 5071

UniProt: O60260

Pathways: Autophagy, Ubiquitin Proteasome Pathway