SNCA antibody (pSer129)

Catalog No. ABIN361526

The Rabbit Polyclonal anti-SNCA antibody has been validated for WB, ELISA and IHC. It is suitable to detect SNCA in samples from Rat.

Quick Overview for SNCA antibody (pSer129) (ABIN361526)

Target: SNCA (Synuclein, alpha (SNCA))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNCA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-SNCA Antibody

Binding Specificity: pSer129

Specificity: Specific for endogenous levels of the ~15 kDa alpha-synuclein protein phosphorylated at Ser129. Immunolabeling is blocked by preadsorption with the phosphopeptide used as antigen, but not by the corresponding non-phosphopeptide.

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: bovine, canine, non-human primate

Characteristics: Our Alpha Synuclein (ser129) rabbit polyclonal phosphospecific primary antibody is produced in-house. It detects Alpha Synuclein (ser129) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB, IHC.

Purification: Prepared from pooled rabbit serum by affinity purification via sequential chromatography on phospho and non-phosphopeptide affinity columns.

Immunogen: Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser129 of rat alpha-aynuclein, conjugated to keyhole limpet hemocyanin (KLH).

Isotype: IgG

Application Details

Application Notes:

Dilution Range: WB Brain: 1:1000

Dilution Range: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Storage: -20 °C

Storage Comment: Storage at -20°C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20°C.

Expiry Date: 12 months

Target Details for SNCA

Target: SNCA (Synuclein, alpha (SNCA))

Alternative Name: SNCA

Background:

Synonyms: Alpha synuclein antibody, Alpha-synuclein antibody, Alpha-synuclein, isoform NACP140 antibody, alphaSYN antibody, MGC105443 antibody, MGC110988 antibody, MGC127560 antibody, MGC64356 antibody, NACP antibody, Non A beta component of AD amyloid antibody, Non A4 component of amyloid antibody, Non A4 component of amyloid precursor antibody, Non-A beta component of AD amyloid antibody, Non-A-beta component of alzheimers disease amyloid , precursor of antibody, Non-A4 component of amyloid precursor antibody, Non-A4 component of amyloid, precursor of antibody, OTTHUMP00000218549 antibody, OTTHUMP00000218551 antibody, OTTHUMP00000218552 antibody, OTTHUMP00000218553 antibody, OTTHUMP00000218554 antibody, PARK 1 antibody, PARK 4 antibody, PARK1 antibody, PARK4 antibody, Parkinson disease (autosomal dominant Lewy body) 4 antibody, Parkinson disease familial 1 antibody, SNCA antibody, Snca synuclein alpha (non A4 component of amyloid precursor) antibody, SYN antibody, Synuclein alpha antibody, Synuclein alpha 140 antibody, Synuclein alpha (non A4 component of amyloid precursor) antibody, SYUA_HUMAN antibody

Description Logic: Our Alpha Synuclein (ser129) rabbit polyclonal phosphospecific primary antibody is produced . It detects Alpha Synuclein (ser129) and is antigen affinity purified from pooled serum. It is great for use in ELISA, WB, IHC.

Gene Name Alternatives: SNCA

Molecular Weight: 15 kDa

Gene ID: 29219

UniProt: P37377

Pathways: Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity