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EGFR antibody (AA 1068-1072)

There is 1 publication for this product available. The Rabbit Polyclonal anti-EGFR antibody is suitable to detect EGFR in samples from Human, Mouse and Rat. It has been validated for WB, IHC and IF.
Catalog No. ABIN362622
$350.90
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Shipping to: United States
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Quick Overview for EGFR antibody (AA 1068-1072) (ABIN362622)

Target

See all EGFR Antibodies
EGFR (Epidermal Growth Factor Receptor (EGFR))

Reactivity

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Human, Mouse, Rat

Host

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Rabbit

Clonality

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Polyclonal

Conjugate

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This EGFR antibody is un-conjugated

Application

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • Binding Specificity

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    AA 1068-1072

    Specificity

    The antibody detects endogenous level of total EGFR protein.

    Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.

    Immunogen

    Peptide sequence around AA 1068-1072 (R-Y-S-S-D) derived from Human EGFR. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

    Isotype

    IgG
  • Application Notes

    Western blotting: 1:500-1:1000
    Immunohistochemistry: 1:50-1:100
    Immunofluorescence: 1:100-1:200

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C/-20 °C

    Storage Comment

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Gui, Han, Zhang, Liang, Wang, Xuan, Yu, Shang: "Dimerization of ZIP promotes its transcriptional repressive function and biological activity." in: The international journal of biochemistry & cell biology, Vol. 44, Issue 6, pp. 886-95, (2012) (PubMed).

  • Target

    EGFR (Epidermal Growth Factor Receptor (EGFR))

    Alternative Name

    EGFR

    Background

    Receptor for EGF, but also for other members of the EGF family, as TGF-a, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentia

    Molecular Weight

    175 kDa

    NCBI Accession

    NP_005219

    UniProt

    P00533

    Pathways

    NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
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