CDK2 antibody (AA 158-162)

Catalog No. ABIN362694

There is 1 publication for this product available. The Rabbit Polyclonal anti-CDK2 antibody is suitable to detect CDK2 in samples from Human, Mouse and Rat. It has been validated for WB.

Quick Overview for CDK2 antibody (AA 158-162) (ABIN362694)

Target: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CDK2 Antibody

Binding Specificity: AA 158-162

Specificity: The antibody detects endogenous level of total CDK2 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Peptide sequence around AA 158-162 (T-Y-T-H-E) derived from Human CDK2. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Isotype: IgG

Application Details

Application Notes: Western blotting: 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

References for anti-CDK2 antibody (ABIN362694)

Chen, Evans, Evans: "FAM129B/MINERVA, a novel adherens junction-associated protein, suppresses apoptosis in HeLa cells." in: The Journal of biological chemistry, Vol. 286, Issue 12, pp. 10201-9, (2011) (PubMed).

Target Details for CDK2

Target: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Alternative Name: CDK2

Background: Involved in the control of the cell cycle. Interacts with cyclins A, B1, B3, D, or E. Activity of CDK2 is maximal during S phase and G2.

Molecular Weight: 34 kDa

NCBI Accession: NP_001789

UniProt: P24941

Pathways: PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA