Niban antibody (AA 912-916)
Quick Overview for Niban antibody (AA 912-916) (ABIN363060)
Target
See all Niban (FAM129A) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 912-916
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Specificity
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
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Immunogen
- peptide sequence around AA 912-916 (K-E-G-E-G) derived from Human Niban. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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Isotype
- IgG
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Application Notes
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Western blotting: 1:500-1:1000
Immunofluorescence: 1:100-1:200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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: "AKT-dependent phosphorylation of Niban regulates nucleophosmin- and MDM2-mediated p53 stability and cell apoptosis." in: EMBO reports, Vol. 13, Issue 6, pp. 554-60, (2012) (PubMed).
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- Niban (FAM129A) (Family with Sequence Similarity 129, Member A (FAM129A))
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Alternative Name
- Niban
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Background
- Regulates phosphorylation of a number of proteins involved in translation regulation including EIF2A, EIF4EBP1 and RPS6KB1. May be involved in the endoplasmic reticulum stress response Vill
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Molecular Weight
- 150 kDa
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NCBI Accession
- NP_443198
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UniProt
- Q9BZQ8
Target
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