RAD50 antibody (C-Term)

Catalog No. ABIN363314

The Rabbit Polyclonal anti-RAD50 antibody is suitable to detect RAD50 in samples from Human, Mouse and Hamster. It has been validated for WB and IP.

Quick Overview for RAD50 antibody (C-Term) (ABIN363314)

Target: RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))

Reactivity: Human, Mouse, Hamster

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAD50 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Product Details anti-RAD50 Antibody

Binding Specificity: C-Term

Specificity: Reacts with RAD50 from human, mouse and hamster

Purification: Antiserum

Immunogen: C-terminal mouse RAD50 (604 amino acids).

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
- IP : 1/100 to 1/1 000 - WB : 1/100 to 1/1 000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: , Sodium azide 0.02 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C/-80 °C

Storage Comment: Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.

Target Details for RAD50

Target: RAD50 (RAD50 Homolog (S. Cerevisiae) (RAD50))

Alternative Name: Rad50

Background: Rad50, a 153 kDa protein involved in DNA double strand break repair, is associated with Mre11 and p95 (Nibrin) to form a multiprotein complex involved in the double strand break repair process. Upon DNA damage, Rad50 and Mre11 redistribute and are co-localized within the nucleus of damaged cells.

Pathways: DNA Damage Repair, Protein targeting to Nucleus