MLXIPL antibody (C-Term, Isoform 1)

Catalog No. ABIN363458

The Rabbit Polyclonal anti-MLXIPL antibody has been validated for WB, IP, IHC (p), IF, ChIP and ICC. It is suitable to detect MLXIPL in samples from Human, Rat and Mouse.

Quick Overview for MLXIPL antibody (C-Term, Isoform 1) (ABIN363458)

Target: MLXIPL (MLX Interacting Protein-Like (MLXIPL))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MLXIPL antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP), Immunocytochemistry (ICC)

Product Details anti-MLXIPL Antibody

Binding Specificity: AA 800-852, C-Term, Isoform 1

Specificity: Reacts with human ~93 kDa ChREBP

Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Cross-Reactivity (Details): May cross react with protein from mouse and rat (83 % sequence homology). Not tested in other species.

Purification: Antigen affinity purified

Immunogen: C-terminal synthetic peptide made to the human ChREBP protein sequence (between residues 800-852). [Uniprot# Q9NP71, isoform 1/alpha]

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
ChIP (1:10 - 1:500) ICC/ IF (1:100 - 1:500) IHC - P(1:100) IP (1:10 - 1:500) WB(1:1000)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Tris-citrate/phosphate, pH 7-8, Sodium azide 0.01 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 6 months

Target Details for MLXIPL

Target: MLXIPL (MLX Interacting Protein-Like (MLXIPL))

Alternative Name: Carbohydrate-Responsive Element-Binding Protein (ChREBP)

Background: ChREBP is a transcription factor involved in activating genes that encode enzymes of fatty acid biosynthesis in liver and adipose.This protein may have relevance to lipid metabolism, obesity, and type II diabetes.

Gene ID: 51085

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process