LC3B antibody (N-Term)
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- Target See all LC3B (MAP1LC3B) Antibodies
- LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Cow
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This LC3B antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunoelectron Microscopy (IEM)
- Specificity
- Reacts with LC3B from human, mouse, rat and bovine and Zebrafish
- Cross-Reactivity (Details)
- Other species have not been tested.
- Purification
- Antigen affinity purified
- Immunogen
- Synthetic peptide made to the N-terminal region of the human LC3, isoform B protein
- Top Product
- Discover our top product MAP1LC3B Primary Antibody
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- Application Notes
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
ICC/IF(1:2000) FC (1:200) IHC (1:400) WB (1:1000) - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS, Sodium azide 0.05 %
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C/-80 °C
- Storage Comment
- Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
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- Target
- LC3B (MAP1LC3B) (Microtubule-Associated Protein 1 Light Chain 3 beta (MAP1LC3B))
- Alternative Name
- Light Chain 3 beta (LC3B) (MAP1LC3B Products)
- Synonyms
- ATG8F antibody, LC3B antibody, MAP1A/1BLC3 antibody, MAP1LC3B-a antibody, Map1lc3 antibody, Mpl3 antibody, zbs559 antibody, 1010001C15Rik antibody, Atg8 antibody, LC3b antibody, zgc:56434 antibody, wu:fb60g11 antibody, map1lc3b antibody, MGC76283 antibody, MAP1LC3B antibody, microtubule associated protein 1 light chain 3 beta antibody, microtubule-associated protein 1 light chain 3 beta antibody, microtubule associated protein 1 light chain 3 beta L homeolog antibody, MAP1LC3B antibody, Map1lc3b antibody, map1lc3b antibody, map1lc3b.L antibody
- Background
- Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.
- Gene ID
- 81631
- Pathways
- Autophagy
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