CD80 antibody (APC)
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- Target See all CD80 Antibodies
- CD80
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Reactivity
- Mouse
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- This CD80 antibody is conjugated to APC
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Application
- Flow Cytometry (FACS)
- Specificity
- This antibody recognises CD80/B7-1 (Mr. 45-47 kDa)
- Characteristics
- Synonyms: CD28LG, CD28LG1, LAB7, BB1, Activation B7-1 antigen, B7.1, T-lymphocyte activationantigen CD80, CTLA-4 counter-receptor B7.1
- Clone
- 1G10
- Isotype
- IgG2a
- Top Product
- Discover our top product CD80 Primary Antibody
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anti-CD80 (CD80) (AA 35-288) antibody
CD80 Reactivity: Human FACS, ELISA, IHC Host: Mouse Monoclonal 1G3D7 unconjugated
anti-CD80 (CD80) antibodyCD80 Reactivity: Mouse, Dog FACS, IP, IHC (fro) Host: Armenian Hamster Monoclonal 16-10A1 unconjugated
anti-CD80 (CD80) (AA 38-246) antibodyCD80 Reactivity: Mouse WB, IP, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-CD80 (CD80) (Extracellular Domain) antibodyCD80 Reactivity: Human FACS, IP Host: Mouse Monoclonal MEM-233 unconjugated
anti-CD80 (CD80) (AA 251-321) antibodyCD80 Reactivity: Human, Mouse, Rat WB, ELISA, IHC (p), ICC, IHC (fro), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated
anti-CD80 (CD80) (Extracellular Domain) antibody (FITC)CD80 Reactivity: Human FACS Host: Mouse Monoclonal MEM-233 FITC
anti-CD80 (CD80) (Extracellular Domain) antibody (PerCP)CD80 Reactivity: Human FACS Host: Mouse Monoclonal MEM-233 PerCP
anti-CD80 (CD80) (Extracellular Domain) antibody (APC)CD80 Reactivity: Human FACS Host: Mouse Monoclonal MEM-233 APC
anti-CD80 (CD80) (Extracellular Domain) antibody (PE)CD80 Reactivity: Human FACS Host: Mouse Monoclonal MEM-233 PE
anti-CD80 (CD80) antibodyCD80 Reactivity: Human ELISA, IHC, ICC Host: Mouse Monoclonal 2A2 unconjugated
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- Application Notes
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Flow Cytometry: < / = 0.2 μg/10^6 cells. (Ref.2,7)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.1 mg/mL
- Buffer
- PBS containing 0.09 % Sodium Azide as preservative and a stabilizing agent.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
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Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - Expiry Date
- 12 months
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- Target
- CD80
- Alternative Name
- CD80 (CD80 Products)
- Background
- CD80 (B7-1) is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is constitutively expressed by dendritic cells, monocytes, and peritoneal macrophages. Expression of CD80 on B cells is upregulated after activation by various means including stimulation by LPS, IL-4, and surface Ig receptor cross linking with peak expression occurring between 48 and 72 hours postactivation. (Ref.1-4) The interaction of CD80/B7-1 with its ligands, CD28 and CD152/CTLA-4, provides a potent costimulatory signal for T cells activated through the CD3/T cell receptor complex. (Ref.5,6). This Monoclonal antibody 1G10 blocks binding of CTLA-4 to CD80, but it does not block stimulation of T cells by natural antigenpresenting cells. (Ref.2,7).Synonyms: Activation B7-1 antigen, B7-1, B7.1, BB1, CD28LG, CD28LG1, CTLA-4 counter-receptor B7.1, LAB7, T-lymphocyte activation antigen CD80
- Gene ID
- 12519
- UniProt
- Q00609
- Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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