Ly6C antibody
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- Target See all Ly6C (Ly-6C) products
- Ly6C (Ly-6C) (Ly-6C)
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Reactivity
- Mouse
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- This Ly6C antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
- Specificity
- This antibody is specific to Murine Ly-6C (Mr. 18 kDa)
- Characteristics
- Synonyms: Lymphocyte antigen 6C2, Ly-6C2, Ly6C2, Mouse Macrophage Marker
- Purification
- Purified
- Clone
- HK1-4
- Isotype
- IgG2c
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- Application Notes
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Flow Cytometry: < / = 1 μg/10^6 cells. (Ref.1,2)Immunohistochemistry on Frozen Sections. (Ref.5)In vitro Activation of T Lymphocytes. (Ref.1,2)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.
- Storage
- 4 °C/-20 °C
- Storage Comment
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - Expiry Date
- 12 months
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- Target
- Ly6C (Ly-6C) (Ly-6C)
- Alternative Name
- Ly6c (Ly-6C Products)
- Background
- Ly-6C is a member of the Ly-6 multigene family of type V glycophosphatidylinositol-anchored cell surface proteins. It is expressed on bone marrow cells, monocytes/macrophages, neutrophils, endothelial cells, and T-cell subsets. Mice with the Ly-6.2 allotype (e.g., AKR, C57BL, C57BR, C57L, DBA/2, PL, SJL, SWR, 129) have subsets of CD4+Ly-6C+ and CD8+Ly-6C+ cells, while Ly-6.1 strains (e.g., A, BALB/c, CBA, C3H/He, DBA/1, NZB) have only CD8+Ly-6C+ lymphocytes. Ly-6C may play a role in the development and maturation of lymphocytes. (Ref.1-4)Synonyms: Ly-6C2, Ly6C2, Lymphocyte antigen 6C2, Mouse Macrophage Marker
- Gene ID
- 100041546
- UniProt
- P09568
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