CD79b antibody

Catalog No. ABIN371130

The Hamster Monoclonal anti-CD79b antibody (Clone HM79-12) (ABIN371130) specifically detects CD79b in WB, FACS, IP and IHC (fro). The antibody is reactive with Mouse samples.

Quick Overview for CD79b antibody (ABIN371130)

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Reactivity: Mouse

Host: Hamster

Clonality: Monoclonal

Conjugate: This CD79b antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: HM79-12

Product Details anti-CD79b Antibody

Specificity: This antibody recognises beta chain of the mouse B-cell receptor (Mr. 23 kDa).

Characteristics: Synonyms: B29, IGB, B-Cell marker, B-cell antigen receptor complex-associated protein beta-chain,B-cell-specific glycoprotein B29, Immunoglobulin-associated B29 protein

Purification: Purified

Isotype: IgG

Application Details

Application Notes: Flow Cytometry: < / = 1 μg/10^6 cells. (Ref.1,2)Immunoprecipitation. Immunohistochemistry on Frozen Sections. (Ref.3)Western Blotting.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for CD79b

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Alternative Name: CD79b

Background: Murine CD79 is a 23/21 kDa disulfide-linked heterodimer composed of an alpha chain (CD79a/mb-1) and a beta chain (CD79b/B29) that associates non-covalently with membrane immunoglobulin (Ig) to form the B cell receptor (BCR) complex. Its expression is restricted to B lymphocytes, first appearing on the surface at the pro-B cell stage prior to productive Ig gene rearrangements and remaining through all stages of B-cell differentiation prior to plasma cells. It has been proposed that the CD79 complex on pro-B cell surfaces may function to induce early B-cell differentiation. (Ref.1)Synonyms: B-Cell marker, B-cell antigen receptor complex-associated protein beta-chain, B-cell-specific glycoprotein B29, B29, IGB, Immunoglobulin-associated B29 protein

Gene ID: 15985

UniProt: P15530

Pathways: BCR Signaling