LAMP2 antibody

Catalog No. ABIN371202

The Rat Monoclonal anti-LAMP2 antibody (Clone ABL-93) (ABIN371202) specifically detects LAMP2 in FACS, IP and IHC (fro). The antibody is reactive with Mouse samples.

Quick Overview for LAMP2 antibody (ABIN371202)

Target: LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This LAMP2 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: ABL-93

Product Details anti-LAMP2 Antibody

Specificity: This antibody is specific to CD107b/LAMP-2 (Mr 110-120 kDa with a core protein of Mr ~40 kDa).

Characteristics: Synonyms: LAMP-2, LAMP-2C, LAMPB, Lysosome-associated membrane glycoprotein 2

Purification: Purified

Immunogen: Glycoproteins purified from BALB/c mouse embryo 3T3 cell line. (Ref. 1)

Isotype: IgG2a

Application Details

Application Notes: Flow Cytometry: < / = 1 μg/10^6 cells. Immunohistochemistry (Acetone-Fixed, Frozen Tissue Sections only). (Ref.2,5)Immunoprecipitation. (Ref.2)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for LAMP2

Target: LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))

Alternative Name: CD107b / LAMP2

Background: CD107b, also known as lysosomal-associated membrane protein 2 (LAMP-2), is a heavily glycosylated, type I transmembrane protein that constitutes one of the two major sialoglycoproteins on lysosomal membranes that can be used to distinguish lysosomes from other organelles. (Ref.1) CD107b is similar in structure to Mac-1 and is expressed primarily on epithelial cells and macrophages in a variety of organs in normal and Beige mutant mice. (Ref.2)Synonyms: LAMP-2, LAMP-2C, LAMPB, Lysosome-associated membrane glycoprotein 2

Gene ID: 16784

UniProt: P17047

Pathways: Autophagy