CD4 antibody
Quick Overview for CD4 antibody (ABIN371333)
Target
See all CD4 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Characteristics
- Synonyms: T4/Leu-3, T cell surface glycoprotein CD4, T Cell Surface Antigen T4/Leu3
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Purification
- Purified
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Isotype
- IgG1
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Application Notes
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Flow Cytometry. Immunohistochemistry (Acetone-Fixed, Frozen Tissue Sections only). (Ref.2)Immunoprecipitation. Inhibition of mitogen-induced proliferation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.
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Storage
- 4 °C/-20 °C
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Storage Comment
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. -
Expiry Date
- 12 months
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- CD4
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Alternative Name
- CD4
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Background
- CD4 is a single chain transmembraneous glycoprotein (59 kDa) which belongs to the immunoglobulin superfamily. CD4 is present on a subset of T lymphocytes ("helper/inducer" T cells) and is also expressed at a lower level on monocytes, tissue macrophages and granulocytes. The antigen is involved in binding to MHC class II molecules. The intracellular domain of the antigen is associated with p56lck protein tyrosine kinase.Synonyms: T-cell surface antigen T4/Leu-3, T-cell surface glycoprotein CD4
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UniProt
- Q6Q4G0
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Pathways
- TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
Target
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