ITGA2 antibody
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- Target See all ITGA2 Antibodies
- ITGA2 (Integrin alpha 2 (ITGA2))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This ITGA2 antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunoprecipitation (IP)
- Specificity
- This antibody recognizes CD49b (Mr 200-210 kDa).
- Characteristics
- Synonyms: Integrin alpha-2, ITGA-2, VLA-2 alpha, VLA2, GPIa, Collagen Receptor, Platelet membraneglycoprotein Ia, CD49 antigen-like family member B
- Purification
- Purified
- Clone
- HAS-4
- Isotype
- IgG2a
- Top Product
- Discover our top product ITGA2 Primary Antibody
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- Application Notes
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Flow Cytometry: Identification and enumeration of CD49b+ cells (< / = 1 μg/10^6 cells). Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.1 mg/mL
- Buffer
- 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.
- Storage
- 4 °C/-20 °C
- Storage Comment
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - Expiry Date
- 12 months
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- Target
- ITGA2 (Integrin alpha 2 (ITGA2))
- Alternative Name
- CD49b / ITGA2 (ITGA2 Products)
- Background
- CD49b, a member of the integrin family of extracellular matrix and cell adhesion molecules, is the integrin alpha-2 chain. CD49b associates noncovalently with CD29, the integrin beta-1 subunit, to form the heterodimer integrin a2b1 that binds laminin and collagen. It is expressed on B and T lymphocytes, NK cells, monocytes, platelets, fibroblasts and long-term cultured T cells. CD49b/CD29 mediates the Mg++ dependent adhesion of platelets to collagen. It may also be utilized by fibroblasts for the reorganization of the collagen matrix during would healing.Synonyms: CD49 antigen-like family member B, Collagen Receptor, GPIa, ITGA-2, Integrin alpha-2, Platelet membrane glycoprotein Ia, VLA-2 alpha, VLA2
- Gene ID
- 3673
- UniProt
- P17301
- Pathways
- CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex
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