CD79b antibody

Catalog No. ABIN371571

The Mouse Monoclonal anti-CD79b antibody (Clone CB3-1) (ABIN371571) specifically detects CD79b in FACS, IP and IHC (fro). The antibody is reactive with Human samples.

Quick Overview for CD79b antibody (ABIN371571)

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD79b antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: CB3-1

Product Details anti-CD79b Antibody

Specificity: This antibody reacts with the beta chain of CD79. (Ref.1-4)

Characteristics: Synonyms: B29, IGB, B-Cell marker, B-cell antigen receptor complex-associated protein beta-chain,B-cell-specific glycoprotein B29, Immunoglobulin-associated B29 protein

Purification: Purified

Isotype: IgG1

Application Details

Application Notes: Flow Cytometry: < / = 1 μg/10^6 cells. Immunohistochemistry on Frozen Sections. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: 100 mM Borate Buffered Saline, pH 8.2. No preservatives or amine-containing buffer salts added.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for CD79b

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Alternative Name: CD79b

Background: CD79 is a 23/21 disulfide-linked heterodimer composed of an alpha chain (CD79a/mb-1) and a beta chain (CD79b/B29). CD79b is the B cell antigen receptor Ig beta chain (BCR Ig beta), which associates with B cell antigen receptor Ig alpha chain to form a functional heterodimer that interacts with membrane immunoglobulin (mIg). The mIgM component binds antigen and the Ig alpha/Ig beta heterodimer tranduces signals. CD79 beta is a B cell specific marker, valuable for the detection of B cells at all maturation stages.Synonyms: B-Cell marker, B-cell antigen receptor complex-associated protein beta-chain, B-cell-specific glycoprotein B29, B29, IGB, Immunoglobulin-associated B29 protein

Gene ID: 974

UniProt: P40259

Pathways: BCR Signaling