FKBP4 antibody (N-Term)

Catalog No. ABIN371865

The Mouse Monoclonal anti-FKBP4 antibody (Clone AT4D3) (ABIN371865) specifically detects FKBP4 in WB, IHC (p) and EIA. The antibody is reactive with Human samples.

Quick Overview for FKBP4 antibody (N-Term) (ABIN371865)

Target: FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FKBP4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: AT4D3

Product Details anti-FKBP4 Antibody

Binding Specificity: AA 1-459, N-Term

Specificity: The antibody recognizes Human FKBP4. Other species not tested.

Characteristics: Synonyms: FK506-binding protein 4, FKBP52 protein, FKBP59, p59 protein, Peptidyl-prolyl cis-transisomerase, PPIase, HSP-binding immunophilin, HBI, 52 kDa FK506-binding protein,Rotamase

Purification: Protein-G affinity chromatography

Immunogen: Recombinant human FKBP4 (1-459 aa) purified from E. coli

Isotype: IgG2b

Application Details

Application Notes: ELISA. Western blot (1: 1,000 - 1: 2,000). Immunohistochemistry on Paraffin embedded tissue (1: 50).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS buffer pH 7.4 with 0.09 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C or -70 °Cfor longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for FKBP4

Target: FKBP4 (FK506 Binding Protein 4, 59kDa (FKBP4))

Alternative Name: FKBP4

Background: FKBP4, also known as FKBP52, is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. It is a component of unactivated mammalian steroid receptor complexes and may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors. It interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes.Synonyms: 52 kDa FK506-binding protein, FK506-binding protein 4, FKBP52 protein, FKBP59, HBI, HSP-binding immunophilin, PPIase, Peptidyl-prolyl cis-trans isomerase, Rotamase, p59 protein

Gene ID: 2288

UniProt: Q02790

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway