CSNK1A1 antibody (N-Term)

Catalog No. ABIN371879

The Mouse Monoclonal anti-CSNK1A1 antibody is suitable to detect CSNK1A1 in samples from Human. It has been validated for WB and EIA.

Quick Overview for CSNK1A1 antibody (N-Term) (ABIN371879)

Target: CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CSNK1A1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: AT2E2

Product Details anti-CSNK1A1 Antibody

Binding Specificity: AA 1-337, N-Term

Specificity: The antibody recognizes Human Casein Kinase 1 alpha. Other species not tested.

Characteristics: Synonyms: CKI-alpha, CSNK1A1, CK1

Purification: Protein-G affinity chromatography

Immunogen: Recombinant human Casein Kinase 1 alpha (1-337 aa) purified from E. coli

Isotype: IgG2b

Application Details

Application Notes: ELISA. Western blot (1: 1000 - 1: 2000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C or -70 °Cfor longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for CSNK1A1

Target: CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

Alternative Name: Casein Kinase I alpha

Background: Caseine Kinase 1 alpha belongs to the protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily. CK1 isoforms (alpha, beta, gamma, delta, epsilon) and their splice variants are involved in diverse cellular processes including membrane trafficking, circadian rhythm, cell cycle progression, chromosome segregation, apoptosis and cellular differentiation. Perhaps it can phosphorylate a large number of proteins and is involved in Wnt signaling where it phosphorylates CTNNB1 on Ser45. Caseine kinase 1 alpha also interacts with the Axin complex.Synonyms: CK1, CKI-alpha, CSNK1A1

Gene ID: 1452

UniProt: P48729

Pathways: WNT Signaling, Hedgehog Signaling