CYTIP antibody (N-Term)

Catalog No. ABIN374184

This anti-CYTIP antibody is a Goat Polyclonal antibody detecting CYTIP in WB. Suitable for Human.

Quick Overview for CYTIP antibody (N-Term) (ABIN374184)

Target: CYTIP (Cytohesin 1 Interacting Protein (CYTIP))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This CYTIP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CYTIP Antibody

Binding Specificity: N-Term

Sequence: SLQRLLQHSS NGN-C

Specificity: This antibody detects CYBR / PSCDBP at N-term.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.

Immunogen: Peptide from N Terminus of the protein sequence according to NP_004279.3 Genename: CYTIP

Application Details

Application Notes: Peptide ELISA: Detection Limit: 1/16000. Western blot: 0.5-2 μg/mL. Detects a band of Approx 38 kDa in lysates of cell line MOLT4.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CYTIP

Target: CYTIP (Cytohesin 1 Interacting Protein (CYTIP))

Alternative Name: CYTIP / PSCDBP

Background: This protein contains 2 leucine zipper domains and a putative C-terminal nuclear targeting signal, and it does not have any hydrophobic regions. It is expressed weakly in resting NK and T cells. It and cytohesin-1 physically interact through their coiled-coil domains. Cytohesin-1, in addition to its role in cell adhesion, is a guanine nucleotide-exchange protein activator of ARF GTPases.Synonyms: CASP, CYBR, Cytohesin binder and regulator, Cytohesin-associated scaffolding protein, Cytohesin-binding protein HE, Cytohesin-interacting protein, PSCDBP, Pleckstrin homology Sec7 and coiled-coil domains-binding protein

Molecular Weight: 40.0kDa according to NP_004279.3.

Gene ID: 9595

NCBI Accession: NP_004279

UniProt: O60759