ADAP2 antibody (C-Term)

Catalog No. ABIN374365

This Goat Polyclonal antibody specifically detects ADAP2 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for ADAP2 antibody (C-Term) (ABIN374365)

Target: ADAP2 (ArfGAP with Dual PH Domains 2 (ADAP2))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This ADAP2 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ADAP2 Antibody

Binding Specificity: C-Term

Sequence: C-RLTASTESGR SSR

Specificity: This antibody detects ADAP2 / CENTA2 at C-term.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide

Immunogen: Peptide from the C Terminus of the protein sequence according to NP_060874.1. Genename: ADAP2

Application Details

Application Notes: Peptide ELISA: Limit dilution 1: 32000. Immunohistochemistry: 5-10 μg/mL. In paraffin embedded Human Placenta shows trongstaining of cytoplasm in syncytiotrophoblasts.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C.

Target Details for ADAP2

Target: ADAP2 (ArfGAP with Dual PH Domains 2 (ADAP2))

Alternative Name: ADAP2 / CENTA2

Background: Centaurin alpha 2 is a potential GTPase-activating protein for the ADP ribosylation factor family. It binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4). It possesses a stoichiometry of two binding sites for InsP4 with identical affinity.Synonyms: Arf-GAP with dual PH domain-containing protein 2, Centaurin alpha 2, Centaurin-alpha-2

Gene ID: 55803

NCBI Accession: NP_060874

UniProt: Q9NPF8