ARHGEF5 antibody (Internal Region)

Catalog No. ABIN374647

This Goat Polyclonal antibody specifically detects ARHGEF5 in WB. It exhibits reactivity toward Human.

Quick Overview for ARHGEF5 antibody (Internal Region) (ABIN374647)

Target: ARHGEF5 (rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This ARHGEF5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ARHGEF5 Antibody

Binding Specificity: Internal Region

Specificity: This antibody reacts to ARHGEF5.

Purification: Affinity chromatography

Immunogen: Peptide with sequence C-DKEIDQNSQQEE, from the internal region of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/16000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ARHGEF5

Target: ARHGEF5 (rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5))

Alternative Name: ARHGEF5 / TIM

Background: Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. ARHGEF5 may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization.Synonyms: Guanine nucleotide regulatory protein TIM, Oncogene TIM, Rho guanine nucleotide exchange factor 5, Transforming immortalized mammary oncogene, p60 TIM

Gene ID: 7984, 9606

UniProt: Q12774