ARHGEF5 antibody (AA 160-240)

Catalog No. ABIN7225104

The Rabbit Polyclonal anti-ARHGEF5 antibody is suitable to detect ARHGEF5 in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for ARHGEF5 antibody (AA 160-240) (ABIN7225104)

Target: ARHGEF5 (rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARHGEF5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ARHGEF5 Antibody

Binding Specificity: AA 160-240

Purpose: Rabbit Anti-Oncogene TIM Polyclonal Antibody

Specificity: Oncogene TIM Polyclonal Antibody detects endogenous levels of Oncogene TIM protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Oncogene TIM at AA range: 160-240

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ARHGEF5

Target: ARHGEF5 (rho Guanine Nucleotide Exchange Factor (GEF) 5 (ARHGEF5))

Alternative Name: Oncogene TIM

Background: ARHGEF5, TIM, Rho guanine nucleotide exchange factor 5, Ephexin-3, Guanine nucleotide regulatory protein TIM, Oncogene TIM, Transforming immortalized mammary oncogene, p60 TIMRho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The protein encoded by ARHGEF5 (Rho guanine nucleotide exchange factor 5) may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization.

Molecular Weight: 60kD

Gene ID: 7984

UniProt: Q12774