Kallikrein 2 antibody (Internal Region)

Catalog No. ABIN374827

This Goat Polyclonal antibody specifically detects Kallikrein 2 in WB, IHC (p) and EIA. It exhibits reactivity toward Human.

Quick Overview for Kallikrein 2 antibody (Internal Region) (ABIN374827)

Target: Kallikrein 2 (KLK2)

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This Kallikrein 2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Product Details anti-Kallikrein 2 Antibody

Binding Specificity: Internal Region

Sequence: C-KHQSLRPDED SSHD

Specificity: This antibody is expected to recognize both reported isoforms of Human KLK2 (NP_005542.1, NP_001002231.1).

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the internal region of the protein sequence according to NP_005542.1, NP_001002231.1. Genename: KLK2

Application Details

Application Notes: Peptide ELISA: 1/16000. Western Blot: 0.1 - 0.3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Tris buffered saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Kallikrein 2

Target: Kallikrein 2 (KLK2)

Alternative Name: KLK2 / Kallikrein-2

Background: Kallikreins (KLKs) are a subgroup of trypsin-like serine proteases and are implicated in carcinogenesis. Kallikrein 2 is most closely related to Kallikrein 3 (PSA), with 78 % identity and with kallikrein 1, at 68 % identity. Like Kallikrein 3, Kallikrein 2 is found in greatest abundance in the prostate, but at much lower levels than Kallikrein 3. In addition, Kallikrein 2 seems to be more labile than Kallikrein 1 or Kallikrein 3 and is often found in a cleaved form. Kallikrein 2 is inhibited by Protein C Inhibitor (PCI).Synonyms: Glandular kallikrein-1, Kallikrein 2, Kallikrein2, Tissue kallikrein-2, hGK-1, hK2

Gene ID: 3817

NCBI Accession: NP_001002231

UniProt: P20151

Pathways: Complement System