ERAP2 antibody (Internal Region)

Catalog No. ABIN374998

This Goat Polyclonal antibody specifically detects ERAP2 in WB and EIA. It exhibits reactivity toward Human, Cow and Dog.

Quick Overview for ERAP2 antibody (Internal Region) (ABIN374998)

Target: ERAP2 (Endoplasmic Reticulum Aminopeptidase 2 (ERAP2))

Reactivity: Human, Cow, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This ERAP2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-ERAP2 Antibody

Binding Specificity: Internal Region

Specificity: This antibody reacts to ERAP2.

Cross-Reactivity (Details): Species reactivity (expected):Canine, Bovine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogen: Peptide with sequence C-QYLKKFSYRNAKND, from the internal region of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/16000. Western Blot: 0.5 - 1.5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for ERAP2

Target: ERAP2 (Endoplasmic Reticulum Aminopeptidase 2 (ERAP2))

Alternative Name: ERAP2 / LRAP

Background: ERAP2 is an aminopeptidase that plays a central role in peptide trimming. Major histocompatibility complex (MHC) class I molecules rely on aminopeptidases such as ERAP2 to trim precursors to antigenic peptides in the endoplasmic reticulum (ER) following cleavage in the cytoplasm by tripeptidyl peptidase II. ERAP2 preferentially hydrolyzes the basic residues Arg and Lys.Synonyms: Endoplasmic reticulum aminopeptidase 2, L-RAP, Leukocyte-derived arginine aminopeptidase

Gene ID: 64167

NCBI Accession: NP_001123612

UniProt: Q6P179