ERAP2 antibody

Catalog No. ABIN7228424

This Rabbit Polyclonal antibody specifically detects ERAP2 in WB and ELISA. It exhibits reactivity toward Human.

Quick Overview for ERAP2 antibody (ABIN7228424)

Target: ERAP2 (Endoplasmic Reticulum Aminopeptidase 2 (ERAP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ERAP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ERAP2 Antibody

Purpose: Rabbit Anti-ERAP2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of ERAP2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human ERAP2 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ERAP2

Target: ERAP2 (Endoplasmic Reticulum Aminopeptidase 2 (ERAP2))

Alternative Name: ERAP2

Background: Endoplasmic reticulum aminopeptidase 2, Leukocyte-derived arginine aminopeptidase, L-RAPERAP2 encodes a zinc metalloaminopeptidase of the M1 protease family that resides in the endoplasmic reticulum and functions in N-terminal trimming antigenic epitopes for presentation by major histocompatibility complex (MHC) class I molecules. Certain mutations in this gene are associated with the inflammatory arthritis syndrome ankylosing spondylitis and pre-eclampsia. This gene is located adjacent to a closely related aminopeptidase gene on chromosome 5.

Molecular Weight: 105kD

Gene ID: 64167

UniProt: Q6P179